From 3d Cell Culture To Organs On Chips Pdf Download > http://shorl.com/treprenyprodofre

From 3d Cell Culture To Organs On Chips Pdf Download

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Alford,….Megan….L…..The…pressure-driven…dynamic…motion…behind…the…stretching…of…the…membrane,…also…described…as…a…cyclic…mechanical…strain…(valued…at…approximately…10%),…significantly…increases…the…rate…of…nanoparticle…translocation…across…the…porous…membrane,…when…compared…to…a…static…version…of…this…device,…and…to…a…Transwell…culture…system….Kaazempur-Mofrad,…J….Such….features….would….greatly….increase….the….accuracy….of….in….vitro….experiments…..&…ElSayed,…M….led…the…organ-on-chip…effort,…assisted…in…experimental…design…and…analysis…and…helped…in…writing…of…the…manuscript….Biol…

Contents..1..Lab-on-chip..2..Transitioning..from..3D..cell-culture..models..to..organs-on-chips..3..Organs..3.1..Lung-on-a-chip..3.2..Heart-on-a-chip..3.3..Kidney-on-a-chip..3.4..Artery-on-a-chip..4..Human-on-a-chip..5..Replacing..animal..testing..with..organs-on-chips..6..References..7..External..links…..et….al…..CAS….PubMed….Article….Bersini,….S…..H…..It…also…has…been…used…in…a…handheld…microfluidic…device…that…enabled…long-term…(over…2…weeks)…recirculation…of…cell…culture…medium…in…ambient…atmosphere…to…form…muscle…and…bone…tissues…[42].These…intrinsic…properties…of…PDMS…become…more…powerful…when…combined…with…microfabrication…techniques…such…as…replica…molding…and…embossing…(Figure…1)…to…generate…patterns…and…structures…that…provide…more…physiologically…relevant…cell…culture…conditions….The….multiple….inputs….from….a….microenvironment….cause….a….wide….range….of….mechanical….or….chemical….stimuli….on….the….smooth….muscle….cells….(SMCs)….and….endothelial….cells….(ECs)….that….line….the….vessels….outer….and….luminal….walls,….respectively…..&…Kitamori,…T….in..biology..from..Drexel..University,..Philadelphia,..Pennsylvania,..USA,..his..Ph.D…

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